Skin T-cells play a central role in the maintenance of a highly dynamic system of homeostasis. They are a sizable population in the tissue and the majority of them have a regulatory phenotype. Diseases such as cutaneous T-cell lymphoma (CTCL) illustrate the strength of these cells and their potential to cause harm. This research project is aimed to understand the mechanisms involved in the emergence of malignant T-cell clones in CTCL and their dependance of adjacent cells for survival and resilience. As most CTCL patients respond to UV-based phototherapy, we are interested in exploring the cellular response triggered by UV with the goal of finding new avenues for therapeutic intervention.
I studied biology and immunology in my home country Mexico before moving to Europe to obtain my doctoral degree at the Medical University of Graz. I’m a senior postdoctoral fellow in the Department of Dermatology and I’m interested in the dynamics and characteristics of the immune cells that populate the skin, their role in homeostasis, and the disturbances that lead to inflammatory and neoplastic disease. In the last years, my research has given me the opportunity to work internationally with leading scientists, extraordinary clinicians and noble-minded patients to address challenging questions on the nature of disease and the action mechanisms of current and innovative treatments.
pablo.vieyra-garcia(at)medunigraz.at
ORCID ID 0000-0001-7101-9313
Twitter @pablovieyra
